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Jess Byun
Education
PhD. Bioinformatics and Computational Biology
University of North Carolina
Chapel Hill, NC
current - 2021
- Advisor: Doug Phanstiel
MS. Biomedical Informatics
University of Utah
Salt Lake City, UT
2021 - 2019
- Advisor: Deborah Neklason
BS. Chemistry
University of Utah
Salt Lake City, UT
2014 - 2010
RESEARCH and WORK EXPERIENCE
Graduate Research Assistant
University of North Carolina
Chapel Hill, NC
current - 2021
- Discovering the genetic variation on mRNA splicing in response to cartilage matrix damage
- Optimize gene-editing protocols using CRISPR technology to validate discovered risk genes.
Graduate Research Assistant
Huntsman Cancer Institute
Salt Lake City, UT
2021 - 2019
- Led project of analyzing copy number variations in rare cancer by utilizing methylation array
- Contributed to a project in the large family inherited genetic studies using WGS and SNP genotyping
- Developed target discovery on Lynch syndrome germline mutation by utilizing RNA-seq and single-cell OMICs approaches
Scientist-Chemist
Navigen Pharmaceutical
Salt Lake City, UT
2019 - 2016
- Developed D-peptide drugs of Human Immunodeficiency Virus (HIV), Respiratory Syncytial Virus (RSV), Ebola and Tumor necrosis factor α (TNF α)-Synthesize both manually and automatically
Research Assistant
University of Utah
Salt Lake City, UT
2019 - 2017
- Led a research project of HIV infected T-cell to find receptor genes and Immune-related genes using RNA-seq
- Conducted a research project of HCC risk factors association using RAN-seq
- Contributed an Alzheimer’s disease associated with alternative splicing
Scientist-Chemist
Nutraceutical Corporation
Ogden, UT
2016 - 2015
PUBLICATION
Response eQTLs, chromain accessibility, and 3D chromain structure in chondorcytes provide mechanistic insight into osteoarthritis risk
BioRxiv
N/A
2024
- Kramer NE+, Byun S+, Coryell P, D’Costa S, Thulson E, Kim H, Parkus SM, Bond ML, Klein ER, Shine J, Chubinskaya S, Love MI, Mohlke KL, Diekman BO, Loeser RF, Phanstiel DH. + Co-first
Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes
Under preparation
N/A
2024
- Byun S, Coryell P , Kramer N, D’Costa2, Eliza S, Thulson E, Shine J ,Parkus P, Chubinskaya S, Loeser RF, Diekman BO, Phanstiel PH.
Differential methylation of G-protein coupled receptor signaling genes in gastrointestinal neuroendocrine tumors.
Sci Rep.* 2021 Jun 10;11(1):12303. doi: 10.1038/s41598-021-91934-5.
N/A
2021
- Byun S, Affolter KE, Snow AK, Curtin K, Cannon AR, Cannon-Albright LA, Thota R, Neklason DW.
Differential alternative splicing between hepatocellular carcinoma with normal and elevated serum alpha-fetoprotein
BMC Med Genomics. 2020 Dec 28;13(Suppl 11):194. doi: 10.1186/s12920-020-00836-4.
N/A
2020
- Jin YJ, Aycheh HM, Han S, Chamberlin J, Shin J, Byun S, Lee Y.
The landscape of alternative splicing in HIV-1 infected CD4 T-cells
BMC Med Genomics. 2020 Apr 3;13(Suppl 5):38. doi: 10.1186/s12920-020-0680-7.
N/A
2020
- Byun S+, Han S+, Zheng Y, Planelles V, Lee Y. + Co-first
Differential alternative splicing regulation among hepatocellular carcinoma with different risk factors
BMC Med Genomics. 2019 Dec 20;12(Suppl 8):175. doi: 10.1186/s12920-019-0635-z.
N/A
2019
- Jin YJ+, Byun S+, Han S, Chamberlin J, Kim D, Kim MJ, Lee Y. + Co-first
Effective therapeutic options for elderly patients with hepatocellular carcinoma
Medicine (Baltimore). 2019 Jul;98(30):e16150. doi: 10.1097/MD.0000000000016150.
N/A
2019
- Shin J, Yu JH, Jin YJ, Suh YJ, Kim DH, Byun S, Lee JW
Identification of exon skipping events associated with Alzheimer’s disease in the human hippocampus
BMC Med Genomics. 2019 Jan 31;12(Suppl 1):13. doi: 10.1186/s12920-018-0453-8
N/A
2019
- Han S, Miller JE,Byun S, Kim D, Risacher SL, Saykin AJ, Lee Y, Nho K.
Teaching experience
How to Learn to Code - Instructor
University of North Carolina
Chapel Hill, NC
2023
NC DNA day - Ambassador
University of North Carolina
Chapel Hill, NC
2023
Introduction to statistical modeling - Teaching assistant
University of North Carolina
Chapel Hill, NC
2022
Intro to probability and statistics - Teaching assistant
University of Utah
Salt Lake City, UT
2021
Leadership and Outreach
Korean-American Scientists and Engineers Association (KSEA)
University of North Carolina
N/A
current - 2023
- Served as volunteer coordinator for the KSEA National Math and Science Competition (NMSC) 2023, managing exams, scoring processes, and assisting the awards ceremony to ensure a seamless experience for participants
First-year group mentor- Biological & Biomedical Sciences Program (BBSP)
University of North Carolina
N/A
current - 2022
- Provided welcoming and supportive guidance for new students, offering insights and advice tailored to the unique challenges of their first year in the Ph.D. program
Korean-American Scientists and Engineers Association (KSEA) - Committe member
University of Utah
N/A
2020 - 2011
- Contributed to successfully execute seminars (>4 times a year), NMSC math competition, and supports the chapter operations.
Scholarship, Traineeships, and Awards
NIAMS F31 Grant fellowship (1F31AR083722 - 01A1)
N/A
N/A
current - 2024
GPSG Travel Award
University of North Carolina
N/A
2024
NIGMS T32 Bioinformatics and Computational Biology Training Grant
N/A
N/A
2023 - 2022
Graduate Student Transportation Grant ($1,000)
University of North Carolina
N/A
2023
Poster presentation
Splicing response QTLs identify putative osteoarthritis risk genes
Thurston Arthritis Research Center (TARC) Research Day
Chapel Hill, NC
Nov 2023
Splicing response QTLs identify putative osteoarthritis risk genes
American Society of Human Genetics(ASHG)
Washigton DC
Oct 2023
Splicing response QTLs identify putative osteoarthritis risk genes
The Genetics retreat
Asheville, NC
Sept 2023
The effect of genetic variation on RNA splicing in response to cartilage matrix damage
Chromatin and Epigenetics Symposium
Chapel Hill, NC
Mar 2023
The effect of genetic variation on RNA splicing in response to cartilage matrix damage
Keystone Symposia
British Columbia, Canada
Mar 2023
Fibronectin Fragment Induces Alternative Splicing of Rho GTPase Pathways in Human Articular Chondrocytes
Thurston Arthritis Research Center (TARC) Research Day
Chapel Hill, NC
Oct 2022
Fibronectin Fragment Induces Alternative Splicing of Rho GTPase Pathways in Human Articular Chondrocytes
The Genetics retreat
Wilmington, NC
Sept 2022
Hypoxia Modulates mRNA in Clear Cell Renal Cell Carcinoma (ccRCC)
UNC BBSP
Chapel Hill, NC
Nov 2021
Chromosome 18 loss of heterozygosity in small intestinal neuroendocrine tumor associated with DNA methylation of Gproteinsignaling pathway
Center for Genomic Medicine (CGM) Symposium
Salt Lake City, UT
Jan 2020
The landscape of alternative splicing in risk factors for hepatocellular carcinoma
Translational Bioinformatics Conference (TBC)
Seoul, Korea
Oct 2018
The landscape of alternative splicing in CD4+ T-cells latently infected with HIV-1
Student Poster Competition Walk-School of Medicine Alumni and Medical Community Weekend
Salt Lake City, UT
Sept 2018
Identification of Alternative spliced genes in HIV infected CD4+ T-cells
American Society of Human Genetics(ASHG)
Orlando, FL
Oct 2017
Oral presentation
Splicing response QTLs identify putative osteoarthritis risk genes
The Osteoarthritis and epigenetics
Toronto, Canada
Sept 2024
- Selected by an abstract
Response sQTLs in primary human chondrocytes identify novel putative osteoarthritis risk genes
The Genetics retreat
Myrtle Beach, SC
Oct 2024
- Selected by an abstract